Endocrine Abstracts

Background: Non-alcoholic fatty liver disease (NAFLD) is now the most common liver disease in children and young people. NAFLD can progress to cirrhosis and is associated with cardiometabolic morbidity and mortality, often requiring liver transplant. Brown adipose tissue (BAT) expends energy for thermogenesis when activated by pharmacological agents, e.g. β3-adrenergic receptor agonists, or environmental signals such as cold exposure. We hypothesise that intermittent cold...